Category: Histone Demethylases

2010;53:215C222

2010;53:215C222. are important second messengers in signaling, involved in cell proliferation, cell-cycle regulation, and metabolic function. Intracellular cAMP and cGMP levels are controlled both at their production, by activated adenylyl-cyclase and guanylyl-cyclase, which catalyze conversion of ATP and GTP to cAMP and cGMP, respectively, and at their destruction, by cyclic nucleotide phosphodiesterases (PDEs) [1] (Physique […]

The gene expression profiles of unstimulated CD4+ T cells of all groups were taken as a baseline, to establish whether there is an intrinsic difference between the groups

The gene expression profiles of unstimulated CD4+ T cells of all groups were taken as a baseline, to establish whether there is an intrinsic difference between the groups. downregulated at the gene expression level. Rather an increase in expression of Th1- and Th17-associated genes caused the shift in Th subset outcome. Pertussis or whooping cough, […]